How can I select the appropriate single-cell product for my study?

2026-06-17

The selection of an appropriate single-cell product should be guided by the specific research objective. The table below summarizes recommended products and their key limitations for common applications.

Research Objective

Recommended Product

Key Limitations

Gene expression profiling (fresh or frozen samples)

SeekOne DD 3' scRNA-seq

Not compatible with FFPE samples

Combined T/B cell clonality and transcriptome profiling

SeekOne DD 5' scRNA-seq + V(D)J

For immune profiling, only supports human/mouse primers; not compatible with nuclei samples

Full-length transcript coverage, mutation detection, alternative splicing, and lncRNA analysis

SeekOne DD scFAST-seq (full-length)

rRNA blocker currently supports only human and mouse

FFPE (formalin-fixed paraffin-embedded) samples

SeekOne DD scMLPSeq

Gene coverage is limited by probe panel design; currently supports human only

Chromatin accessibility and transcriptome (multi-omics)

SeekOne DD Multiome ATAC + RNA

Requires nuclei input; fresh samples are recommended

DNA methylation and transcriptome (multi-omics)

SeekOne DD Multiome Methylation + RNA

Requires relatively high sequencing depth

Spatial transcriptomics (true single-cell resolution)

SeekSpace scSpatial-seq

Requires OCT-embedded fresh frozen sections; FFPE is not supported

 

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