What are the key bioinformatic QC metrics for SeekOne DD Single-Cell Multiome ATAC + RNA data?
2026-06-23
Answer:
The SeekOne DD Single-Cell Multiome ATAC + RNA workflow simultaneously profiles chromatin accessibility and transcriptomic information from the same nucleus. The QC report generated by SeekArcTools is primarily divided into:
- Joint metrics
- RNA matrix QC metrics
- ATAC matrix QC metrics
- Peak and TSS enrichment metrics
- ATAC mapping metrics
Because RNA and ATAC modalities are derived from the same barcode, discrepancies between the two modalities may indicate modality-specific library-construction failure, low-complexity libraries, or barcode-level signal imbalance.
Joint Metrics
RNA Matrix QC Metrics
RNA Sequencing QC Metrics
RNA Mapping QC Metrics
RNA Cell-Level QC Metrics
ATAC Matrix QC Metrics
ATAC Sequencing QC Metrics
Cells and Peaks Metrics
Targeting and TSS Enrichment Metrics
ATAC Mapping QC Metrics
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